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This book describes the evolutionary pathways and origins of science policy and innovation studies. Besides, it tries through analyses of highly cited articles that have been cited by other researchers systematically identified the key intellectual development in this area over the past 50 years. The analysis shows that emerging field of science policy and innovation studies how have benefited in the late 1950s and 1960s from a range of disciplines and how its connection with these disciplines has evolved over time. In the mid-1980s, significant parts of policy in the field of science and innovation studies gradually integrating in more coherent area which was focused on the acceptance of evolution economic framework (or Nushumptry), interactive model of innovation process and (a little later) the concept of "innovation systems" and resource based vision (RBV) of the firm. The book is finished through discuss about that "whether the field of science policy and innovation studies is in the early stages of becoming a scientific discipline?"